PhotoHA for Cartilage Restoration
09/08/23
Publication Title:
Improved Cartilage Protection with Low Molecular Weight Hyaluronic Acid Hydrogel
Advanced BioMatrix Products Used:
PhotoHA® Methacrylated Hyaluronic Acid
How the products were used:
The post-traumatic joint experiences a pro-inflammatory milieu, initiating a subtle but deteriorative process in cartilage tissue. This group developed a tissue-penetrating methacrylated hyaluronic acid hydrogel system (using PhotoHA) which crosslinked within cartilage to restore and/or protect the damaged tissue.
Conclusion:
The methacrylated hyaluronic acid hydrogels integrated into the tissue and provided protection of the cartilage matrix. Future work will test this formulation in a preclinical model, with the goal of translating this therapeutic approach for cartilage preservation.
