SpongeCol Scaffold to Study Upregulation
06/03/21
Publication Title:
Fibroblasts Upregulate Expression of Adhesion Molecules and Promote Lymphocyte Retention in 3D Fibroin/Gelatin Scaffolds.
Advanced BioMatrix Products Used:
SpongeCol® Type I Collagen Sponge
How the products were used:
SpongeCol collagen sponges were used as the core for creating 3D scaffolds for implantation.
Conclusion:
"We observed ICAM-1/VCAM-1-dependent adhesion of lymphocytes to fibroblasts cultured in 3D fibroin/gelatin scaffolds, but not on 2D fibroin/gelatin films, suggesting functional reprogramming in stromal cells, when exposed to 3D environment."
Link to the publication:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7988350/#__ffn_sectitle
