VitroCol Coated Transwell Inserts
10/20/23
Publication Title:
Gut Bacteria Promote Proliferation in Benign S/RG/C2 Colorectal Tumour Cells, and Promote Proliferation, Migration and Invasion in malignant HCT116 Cells
Advanced BioMatrix Products Used:
Type I Collagen Hydrogels eBrochure
How the products were used:
VitroCol Type I Human Collagen was used to coat transwell inserts for evaluating tumor cell migration and invasion.
The migratory and invasive potential of HCT116 cells was increased after infection with F. nucleatum; however, no species significantly altered these characteristics in S/RG/C2 cells. These results add to the growing evidence for the involvement of microorganisms in CRC progression and suggest that these interactions may be dependent on tumour cell-specific characteristics.
