Biomimetic 3D Models - Atherosclerosis
09/21/20
Publication Title:
Biomimetic 3D Models for Investigating the Role of Monocytes and Macrophages in Atherosclerosis
Advanced BioMatrix Products Used:
RatCol® Type I Telocollagen (4 mg/ml) from rat tail
Advanced BioMatrix Collagen eBrochure
How the products were used:
RatCol® collagen was formulated to create a 3D hydrogel to help investigate the role of Monocytes and Macrophages in Atherosclerosis.
Abstract:
Our work demonstrated that collagen density in the plaque could be one of the major factors driving atherosclerotic progression via modulation of monocyte and macrophages behaviors.