Cell Collagen Remodeling
02/12/21
Publication Title:
Comparison of Annulus Fibrosus Cell Collagen Remodeling Rates in a Microtissue System
Advanced BioMatrix Products Used:
RatCol® Rat Tail Collagen, 4 mg/ml, #5153-1KIT
How the products were used:
Rat tail collagen was used to create a microtissue in order to study collagen remodeling capacity of Annulus Fibrosus cells.
Article Conclusion:
The MRL/MpJ mice strain and the parental LG/J strain have demonstrated superior regenerative capacities of body tissues, such as ear wound healing and cartilage repair. Many mechanisms have been identified that could potentially explain these regenerative properties, including increased proliferation and migration of cells, increased tenascin expression and increased extracellular matrix production and angiogenesis. Additionally, molecular mechanisms showing regenerative potential in MRL/MpJ have also emerged.
Link to the publication:
https://onlinelibrary.wiley.com/doi/10.1002/jor.24921
