FibriCol for Mechanotransduction
06/07/21
Publication Title:
Cell-Laden Agarose-Collagen Composite Hydrogels for Mechanotransduction Studies
Advanced BioMatrix Products Used:
FibriCol® type I collagen, 10 mg/ml, atelocollagen
How the products were used:
FibriCol® type I collagen, 10 mg/ml, was mixed with agarose to form 3D hydrogels in a mechanotransduction study. This is important because many degenerative and regenerative processes are related to mechanical loading. The interest in understanding how mechanical signals influence cell behavior is in fact shared across disciplines as diverse as cancer and developmental biology, regenerative medicine, tissue engineering, and clinical disciplines such as pulmonology and orthopedics
Article Conclusion:
"Agarose-collagen thus outperforms agarose, mimics native tissues constituted of non-fibrillar matrix and collagens, and allows exploring complex loading in a highly reproducible system."
Link to the publication:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7186378/
