Freeze-FRESH Method for 3D Bioprinting
05/19/21
Publication Title:
Optimization of Freeze-FRESH Methodology for 3D Printing of Microporous Collagen Constructs
Advanced BioMatrix Products Used:
Lifeink® 200 35 mg/ml type I Collagen Bioink
How the products were used:
Lifeink 200 was 3D bioprinted using FRESH printing and freeze-cast in various ways to affect the collagen microporosity. Larger micropores showed greater cell infiltration and metabolic activity.
Article Conclusion:
Constructs with larger micropore size were more stable and showed significantly greater cell infiltration and metabolic activity. Together, these results suggest that the FF method can be customized to guide the design of 3D-printed microporous collagen constructs.
Link to the publication:
https://www.liebertpub.com/doi/abs/10.1089/3dp.2020.0311
