Lifeink 200 Fibrosis Model
09/26/23
Publication Title:
Novel Bioprinted 3D Model to Human Fibrosis Investigation
Advanced BioMatrix Products Used:
Lifeink® 200 35 mg/ml type I Collagen Bioink
How the products were used:
Fibroblasts were printed with Lifeink 200 and then stimulated by TGFB, differentiating them into myofibroblasts with enhanced contractile activity.
The above image is a fibrotic nodule observed by SEM microscopy on the Lifeink® bioprinted structure.
Special thanks to the TPM team for the image.
Article Conclusion:
Overall, these findings demonstrate that it is possible to generate a reproducible and functional 3D platform to mimic fibrosis as key tool for drug discovery and impacting on animal experimentation and reducing costs and time in addressing fibrosis.
Link to the publication:
https://www.sciencedirect.com/science/article/pii/S075333222300937X
