Lifeink 200 with Optical Coherence Tomography
12/29/21
Publication Title:
In Situ Volumetric Imaging and Analysis of FRESH 3D Bioprinted Constructs Using Optical Coherence Tomography
Advanced BioMatrix Products Used:
Lifeink® 200 35 mg/ml type I Collagen Bioink
How the products were used:
Lifeink 200 collagen bioink was 3D bioprinted using FRESH printing. Authors then used an integrated optical coherence tomography (OCT) for in situ volumetric imaging, error detection, and 3D reconstruction.
Article Conclusion:
Authors report "improvements to the Freeform Reversible Embedding of Suspended Hydrogels (FRESH) bioprinting process through new collagen bioink compositions, support bath optical clearing, and machine pathing. This enables high-fidelity 3D volumetric imaging with micron scale resolution over centimeter length scales, the ability to detect a range of print defect types within a 3D volume, and real-time imaging of the printing process at each print layer."
Link to the publication:
https://www.biorxiv.org/content/10.1101/2021.06.30.450389v2
