Microvalve Cell Printing with Collagen
09/17/20
Publication Title:
A Microvalve Cell Printing Technique Using Riboflavin Photosensitizer for Selective Cell Patterning onto a Retinal Chip
Advanced BioMatrix Products Used:
Nutragen® 6 mg/ml type I Atelocollagen
Advanced BioMatrix Collagen eBrochure
How the products were used:
Nutragen® highly purified type I collagen was mixed with cells and 3D printed using a custom microvalve printer. The ink and cells were deposited onto a subretinal chip and photocrosslinked, creating high resolution positioning of cells.
Abstract:
The bioink is coupled with a light-induced collagen photo-crosslinking mechanism. The collagen, mixed with the riboflavin, can be crosslinked after exposure to blue light. The cells printed on the chip remained in the collagen patterns and demonstrated good viability and growth. This technique provided a useful means of delivering cells where high precision, throughput and accuracy is required, such as onto sub-retinal chips.
Link to the publication:
https://www.sciencedirect.com/science/article/pii/S2405886620300245
