PhotoGel and PhotoHA for DLP Printing

Publication Title:

Self-Organization of Long-Lasting Human Endothelial Capillary-Like Networks Guided by DLP Bioprinting

Advanced BioMatrix Products Used: 

PhotoCol® Methacrylated Collagen

PhotoGel® Methacrylated Gelatin

PhotoHA® Methacrylated Hyaluronic Acid

How the products were used:

PhotoGel (methacrylated gelatin), PhotoHA (methacrylated hyaluronic acid) and PhotoCol (methacrylated collagen) were used as bioinks for for 3D-DLP-Bioprinting of endothelial progenitor cells. 

Article Conclusion:

In this work, digital light processing bioprinting is used to encapsulate endothelial progenitor cells (EPCs) in 3D light-cured hydrogel scaffolds to guide them toward vascular network formation. In these scaffolds, EPCs proliferate and self-organize within a few days into branched tubular structures with predefined geometry, forming capillary-like vascular tubes or trees of diameters in the range of 10 to 100 µm.

Link to the publication: 

https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.202302830