PureCol EZ Gel Bioartificial Tendons
03/22/22
Publication Title:
Mechanical Overload Decreases Tenogenic Differentiation Compared to Physiological Load in Bioartificial Tendons
Advanced BioMatrix Products Used:
PureCol® EZ Gel Type I Collagen, Atelocollagen, 3 mg/ml
How the products were used:
PureCol EZ Gel Type I Collagen was used to make bioartificial tendons. Researchers then studied the effects of mechanical overload on the tendons.
Article Conclusion:
Mechanical overload decreases tenogenic differentiation and increases ECM remodelling/inflammation in 3D-stimulated fibroblasts, whereas physiological load may induce opposite effects.
Link to the publication:
https://jbioleng.biomedcentral.com/articles/10.1186/s13036-022-00283-y
