Stiffness effects on HFF and U87 Cell Morphology
06/10/21
Publication Title:
Probing Cellular Response to Topography in Three Dimensions
Advanced BioMatrix Products Used:
CytoSoft® PDMS Soft Substrate Plates
How the products were used:
CytoSoft® Plates (6-well plates with a thin layer of PDMS of a specific stiffness, including 0.2, 0.5, 2, 8, 16, 32 and 64 kPa) were used to evaluate the affect of substrate stiffness on HFF and U87 cell morphology.
Article Conclusion:
The results indicated that the aspect ratios of HFF and U87 cells were unchanged when seeded on substrates ranging in stiffness from 0.5 kPa to 64 kPa.
Link to the publication:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390976/#!po=79.6296
