Cells Stiffen Localized Matrix

Cells Stiffen Localized Matrix

12/09/20

Publication Title:

Dermal Fibroblasts and Triple-Negative Mammary Epithelial Cancer Cells Differentially Stiffen their Local Matrix

 

Advanced BioMatrix Products Used: 

RatCol® Type I Rat Tail Collagen, 4 mg/ml, Telocollagen

Collagen eBrochure

 

How the products were used:

RatCol® type I rat tail collagen was used to embed cells while studying how the cells differentially stiffen their local matrix. 

 

Article Conclusion:

The results suggest that MDAs adapt to the bulk ECM stiffness, while Dermal Fibroblasts regulate local stiffness to levels they intrinsically prefer.

 

Link to the publication:

https://aip.scitation.org/doi/full/10.1063/5.0021030 

 


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