Collagen to Study Diesel Exhaust Particles
08/02/23
Publication Title:
Role of Different Mechanisms in Pro-Inflammatory Responses Triggered by Traffic-Derived Particulate Matter in Human Bronchiolar Epithelial Cells
Advanced BioMatrix Products Used:
PureCol® Type I Collagen, Atelocollagen, 3 mg/ml
How the products were used:
PureCol Type I Collagen was used to coat plates for culturing human bronchial epithelial cells. Researchers studied the adverse effects of diesel exhaust particles on inflammatory responses.
Article Conclusion:
Road tunnel PM caused time-dependent increases in expression of CXCL8, COX2, IL-1α, IL-1β, TNF-α, COX2, PAI-2, CYP1A1, CYP1B1 and HO-1, with fine PM as more potent than coarse PM at early time-points.
Link to the publication:
https://particleandfibretoxicology.biomedcentral.com/articles/10.1186/s12989-023-00542-w
