Collagen Stability Study
02/25/25
In this study, we evaluated the long-term stability of PureCol (3 mg/mL) and Nutragen (6 mg/mL) type I bovine collagen hydrogels in cell culture medium by monitoring changes in stiffness over a 9-day incubation period.
Both hydrogels remained structurally intact, with no visible signs of disintegration. However, both hydrogels exhibited a gradual decrease in stiffness over time.
Particularly, PureCol, the lower-concentration gel, experienced a more pronounced stiffness loss of approximately 48%, whereas Nutragen maintained greater mechanical stability due to its higher collagen concentration.
