Rat Tail Collagen for Microfluidics
02/11/22
Publication Title:
Microfluidic Device Engineered to Study the Trafficking of Multiple Myeloma Cancer Cells Through the Sinusoidal Niche of Bone Marrow
Advanced BioMatrix Products Used:
RatCol® Rat Tail Collagen, 4 mg/ml, #5153-1KIT
How the products were used:
Rat Tail Collagen from Advanced BioMatrix was used to coat a novel microfluidic device. The collagen coating improved adhesion of bone marrow stromal cells. The collagen was also used for culturing BMSC's.
Article Conclusion:
The results suggest that the device can be used to study the physical and secreted factors determining the trafficking of cancer cells through BM. The sinusoidal flow feature of the device provides an integral element for further creating systemic models of cancers that reside or metastasize to the BM niche.
Link to the publication:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795452/
